Singapore

Addressing missing modalities is a critical challenge in multimodal brain tumor segmentation. Most existing approaches merely handle modality-incomplete inputs during inference, assuming a full set of modalities for all training samples. However, this unrealistic assumption limits the usage of abundant modality-incomplete data commonly observed in clinical practice. In this paper, we explore a more practical task of tackling missing modalities during both training and inference. We propose a universal model featuring robust modality reconstruction and prompt-guided modality adaptation. Our mask-reconstruction pre-training enables robust modality-invariant representation learning, during which we design a novel distribution approximation method that supervises the reconstruction of absent modalities without requiring full-modal training data. Afterwards, when adapting our model to the segmentation task, we introduce the complete-then-distill (CTD) paradigm, which first estimates missing modalities in training samples from the available ones, and then distills the knowledge from the reconstructed full-modal representations to enhance the learning process with incomplete modalities. Moreover, we propose prompt-guided modality adaptation to personalize a part of model parameters during CTD, enabling the model to adapt to each distinct modality input scenario through using prompts with rich visual-textual information. Extensive experiments on two brain tumor segmentation benchmarks show our method consistently surpasses previous state-of-the-art approaches under dual-stage missing modality settings across various missing ratios.

AAAI 2026

Tackling Dual-stage Missing Modalities in Brain Tumor Segmentation via Robust Modality Reconstruction and Prompt-guided Modality Adaptation

cv: medical and biological imaging

cv: multi-modal vision

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-23 is the Thirty-Seventh AAAI Conference on Artificial Intelligence. The theme of this conference is to create collaborative bridges within and beyond AI. Like previous AAAI conferences, AAAI-23 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and two new activities: a Bridge Program and a Lab Program. Many of these activities are tailored to the theme of bridges and all are selected according to the highest standards, with additional programs for students and young researchers. 
AAAI is providing you with a conference planner, which you can use to help organize your itinerary of activities. This includes talks to attend in person, talks to attend remotely, breaks with colleagues and your site seeing activities. To access this conference planner, please go to [https://aaai-2023.takemobi.io](https://aaai-2023.takemobi.io).

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AAAI 2023

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines.

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We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-26 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and a range of other activities to be announced.

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We are pleased to announce the Fortieth AAAI Conference on Artificial Intelligence (AAAI-26), which will be held in Singapore EXPO from January 20 to January 27, 2026.

Retrieval-augmented generation (RAG) enhances the reasoning capabilities of large language models (LLMs) by incorporating external knowledge. Among available sources, knowledge graphs (KGs) offer a structured and reliable foundation for factual information, making them increasingly popular in efforts to improve reasoning faithfulness in RAG. Most existing KG-based RAG methods rely on LLMs to extract knowledge from KGs. However, these approaches often require costly fine-tuning and struggle to navigate deep graph structures, limiting their effectiveness in multi-hop reasoning tasks. To address these challenges, we propose Stepwise Contrastive Reasoning (SCR), a lightweight framework that integrates graph structure and textual context for efficient and interpretable RAG over KGs. SCR combines relational message passing layers to encode KG entities with a Transformer encoder for processing question text. It decomposes reasoning into a series of alignment steps. At each step, SCR compares the current topic entity and its neighbors with the question representation, selecting the most relevant entity as the next topic entity. The question is then updated with this entity's textual description. This process continues until the selected entity no longer changes, indicating that the answer entity has been reached. Through stepwise alignment, SCR enables compact models to perform faithful and interpretable reasoning over large-scale KGs. Extensive experiments on several widely used KGQA benchmarks demonstrate that SCR not only achieves state-of-the-art performance but also effectively boosts the capabilities of smaller language models to match those of LLMs.

Stepwise Contrastive Reasoning for Retrieval-Augmented Generation over Knowledge Graphs

The de novo generation of molecules with desirable properties is a critical challenge, where diffusion models are computationally intensive and autoregressive models struggle with error propagation. In this work, we introduce the Graph VQ-Transformer (GVT), a two-stage generative framework that achieves both high accuracy and efficiency. The core of our approach is a novel Graph Vector Quantized Variational Autoencoder (VQ-VAE) that compresses molecular graphs into high-fidelity discrete latent sequences. By synergistically combining a Graph Transformer with canonical Reverse Cuthill-McKee (RCM) node ordering and Rotary Positional Embeddings (RoPE), our VQ-VAE achieves near-perfect reconstruction rates. An autoregressive Transformer is then trained on these discrete latents, effectively converting graph generation into a well-structured sequence modeling problem. Crucially, this mapping of complex graphs to high-fidelity discrete sequences bridges molecular design with the powerful paradigm of large-scale sequence modeling, unlocking potential synergies with Large Language Models (LLMs). Extensive experiments show that GVT achieves state-of-the-art or highly competitive performance across major benchmarks like ZINC250k, MOSES, and GuacaMol, and notably outperforms leading diffusion models on key distribution similarity metrics such as FCD and KL Divergence. With its superior performance, efficiency, and architectural novelty, GVT not only presents a compelling alternative to diffusion models but also establishes a strong new baseline for the field, paving the way for future research in discrete latent-space molecular generation.

Graph VQ-Transformer (GVT): Fast and Accurate Molecular Generation via High-Fidelity Discrete Latents

Recent advances in Time Series Foundation Models (TSFMs) have fundamentally revolutionized general time series analysis across domains like finance, retail, weather, and power. However, how to unlock the hidden capacity of general-purpose TSFMs for wearable activity recognition still remains largely unexplored, given severe sensor annotation scarcity and highly heterogeneous sensor data. To address these challenges, we propose DeepSenseMoE—a novel multi-scale convolution-based Mixture of Experts (MoE) module for parameter-efficient fine-tuning of general-purpose TSFMs to sensor-based activity recognition. DeepSenseMoE integrates three key innovations: (1) Multi-scale convolutional experts with different filter sizes responsible for capturing varying sensor contexts; (2) Shared-expert isolation mechanism compressing common activity knowledge into a single shared expert while reducing redundancy among routed experts; and (3) Hierarchical supervised contrastive alignment guiding experts to further learn discriminative activity features. Extensive experiments on three challenging HAR benchmarks demonstrate DeepSenseMoE's superiority, achieving up to 9.5% accuracy gains over state-of-the-art under few-shot and full-supervised settings, with only <1% additional trainable parameters. We hope that this work may establish a solid foundation to accelerate development and deployment of powerful TSFMs in data-scarce wearable activity recognition tasks while reducing the reliance on labeled sensor data. Code will be released.

DeepSenseMoE: Harnessing Power of Time Series Foundation Models for Few-Shot Human Activity Recognition

Recent camera-based 3D semantic scene completion (SSC) methods have increasingly explored leveraging temporal cues to enrich the features of the current frame. However, while these approaches primarily focus on enhancing in-frame regions, they often struggle to reconstruct critical out-of-frame areas near the sides of the ego-vehicle, although previous frames commonly contain valuable contextual information about these unseen regions. To address this limitation, we propose the Current-Centric Contextual 3D Fusion (C3DFusion) module, which generates hidden region-aware 3D feature geometry by explicitly aligning 3D-lifted point features from both current and historical frames. C3DFusion performs enhanced temporal fusion through two complementary techniques—historical context blurring and current-centric feature densification—which suppress noise from inaccurately warped historical point features by attenuating their scale, and enhance current point features by increasing their volumetric contribution. Simply integrated into standard SSC architectures, C3DFusion demonstrates strong effectiveness, significantly outperforming state-of-the-art methods on the SemanticKITTI and SSCBench-KITTI-360 datasets. Furthermore, it exhibits robust generalization, achieving notable performance gains when applied to other baseline models.

Towards Temporal Fusion Beyond the Field of View for Camera-based Semantic Scene Completion

Remote sensing imagery presents vast, inherently unstructured spatial data, necessitating sophisticated reasoning to interpret complex user intents and contextual relationships beyond simple recognition tasks. In this paper, we aim to construct an Earth observation workflow to handle complex queries by reasoning about spatial context and user intent. As a reasoning workflow, it should autonomously explore and construct its own inference paths, rather than being confined to predefined ground‑truth sequences.
Ideally, its architecture ought to be unified yet generalized, possessing capabilities to perform diverse reasoning tasks through one model without requiring additional fine-tuning.
Existing remote sensing approaches rely on supervised fine-tuning paradigms and task‑specific heads, limiting both autonomous reasoning and unified generalization.
To this end, we propose RemoteReasoner, a unified workflow for geospatial reasoning. The design of RemoteReasoner integrates a multi-modal large language model (MLLM) for interpreting user instructions and localizing targets, together with task transformation strategies that enable multi-granularity tasks, including object-, region-, and pixel-level. 
In contrast to existing methods, our framework is trained with reinforcement learning (RL) to endow the MLLM sufficient reasoning autonomy. 
At the inference stage, our transformation strategies enable diverse task output formats without requiring task-specific decoders or further fine-tuning. Experiments demonstrated that RemoteReasoner achieves state-of-the-art (SOTA) performance across multi-granularity reasoning tasks. Furthermore, it retains the MLLM's inherent generalization capability, demonstrating robust performance on unseen tasks and out-of-distribution categories. 
The model and code will be publicly available once our paper is accepted.

RemoteReasoner: Towards Unifying Geospatial Reasoning Workflow

We study an online linear regression setting in which the observed feature vectors are corrupted by noise and the learner can pay to reduce the noise level. In practice, this may happen for several reasons: for example, because features can be measured more accurately using more expensive equipment, or because data providers can be incentivized to release less private features. Assuming feature vectors are drawn i.i.d. from a fixed but unknown distribution, we measure the learner's regret against the linear predictor minimizing a notion of loss that combines the prediction error and payment. When the mapping between payments and noise covariance is known, we prove that the rate $\sqrt{T}$ is optimal for regret if logarithmic factors are ignored. When the noise covariance is unknown, we show that the optimal regret rate becomes of order $T^{2/3}$ (ignoring log factors). Our analysis leverages matrix martingale concentration, showing that the empirical loss uniformly converges to the expected one for all payments and linear predictors.

Online Linear Regression with Paid Stochastic Features

Model merging has emerged as an efficient technique for expanding large language models (LLMs) by integrating specialized expert models. However, it also introduces a new threat: model merging stealing, where free-riders exploit models through unauthorized model merging.
Unfortunately, existing defense mechanisms fail to provide effective protection. Specifically, we identify three critical protection properties that existing methods fail to simultaneously satisfy: (1) proactively preventing unauthorized merging; (2) ensuring compatibility with general open-source settings; (3) achieving high security with negligible performance loss.
To address the above issues, we propose MergeBarrier, a plug-and-play defense that proactively prevents unauthorized merging. The core design of MergeBarrier is to disrupt the Linear Mode Connectivity (LMC) between the protected model and its homologous counterparts, thereby eliminating the low-loss path required for effective model merging.
Extensive experiments show that MergeBarrier effectively prevents model merging stealing with negligible accuracy loss.

Do Not Merge My Model! Safeguarding Open-Source LLMs Against Unauthorized Model Merging

Recent advances in audio-driven portrait animation have demonstrated impressive capabilities. However, existing methods struggle to align with fine-grained human preferences across multiple dimensions, such as motion naturalness, lip-sync accuracy, and visual quality. This is due to the difficulty of optimizing among competing preference objectives, which often conflict with one another, and the scarcity of large-scale, high-quality datasets with multidimensional preference annotations. To address these, we first introduce Talking-Critic, a multimodal reward model that learns human-aligned reward functions to quantify how well generated videos satisfy multidimensional expectations. Leveraging this model, we curate Talking-NSQ, a large-scale multidimensional human preference dataset containing 410K preference pairs. Finally, we propose Timestep-Layer adaptive multi-expert Preference Optimization (TLPO), a novel framework for aligning diffusion-based portrait animation models with fine-grained, multidimensional preferences. TLPO decouples preferences into specialized expert modules, which are then fused across timesteps and network layers, enabling comprehensive, fine-grained enhancement across all dimensions without mutual interference. Experiments demonstrate that Talking-Critic significantly outperforms existing methods in aligning with human preference ratings. Meanwhile, TLPO achieves substantial improvements over baseline models in lip-sync accuracy, motion naturalness, and visual quality, exhibiting superior performance in both qualitative and quantitative evaluations.

FantasyTalking2: Timestep-Layer Adaptive Preference Optimization for Audio-Driven Portrait Animation

Cell clustering is crucial for uncovering cellular heterogeneity in single-cell RNA sequencing (scRNA-seq) data by identifying cell types and marker genes. Despite its importance, benchmarks for scRNA-seq clustering methods remain fragmented, often lacking standardized protocols and failing to incorporate recent advances in artificial intelligence. To fill these gaps, we present scCluBench, a comprehensive benchmark of clustering algorithms for scRNA-seq data. First, scCluBench provides 36 scRNA-seq datasets collected from diverse public sources, covering multiple tissues, which are uniformly processed and standardized to ensure consistency for systematic evaluation and downstream analyses. To evaluate performance, we collect and reproduce a range of scRNA-seq clustering methods, including traditional, deep learning-based, graph-based, and biological foundation models. We comprehensively evaluate each method both quantitatively and qualitatively, using core performance metrics as well as visualization analyses. Furthermore, we construct representative downstream biological tasks, such as marker gene identification and cell type annotation, to further assess the practical utility. scCluBench then investigates the performance differences and applicability boundaries of various clustering models across diverse analytical tasks, systematically assessing their robustness and scalability in real-world scenarios. Overall, scCluBench offers a standardized and user-friendly benchmark for scRNA-seq clustering, with curated datasets, unified evaluation protocols, and transparent analyses, facilitating informed method selection and providing valuable insights into model generalizability and application scope. All datasets, code, and supplementary resources for scCluBench are available after publication.

scCluBench: Comprehensive Benchmarking of Clustering Algorithms for Single-Cell RNA Sequencing

Large language model (LLM)-based recommender systems have achieved high-quality performance by bridging the discrepancy between the item space and the language space through item tokenization. However, existing item tokenization methods typically require training separate models for each item domain, limiting generalization. Moreover, the diverse distributions and semantics across item domains make it difficult to construct a unified tokenization that preserves domain-specific information. To address these challenges, we propose **UniTok**, a **Uni**fied item **Tok**enization framework that integrates our own mixture-of-experts (MoE) architecture with a series of codebooks to convert items into discrete tokens, enabling scalable tokenization while preserving semantic information across *multiple item domains*. Specifically, items from different domains are first projected into a unified latent space through a shared encoder. They are then routed to *domain-specific* experts to capture the *unique* semantics, while a *shared* expert, which is always active, encodes common knowledge transferable across domains. Additionally, to mitigate *semantic imbalance* across domains, we present a mutual information calibration mechanism, which guides the model towards retaining similar levels of semantic information for each domain. Comprehensive experiments on wide-ranging real-world datasets demonstrate that the proposed UniTok framework is **(a) highly effective:** achieving up to 51.89\% improvements over strong benchmarks, **(b) theoretically sound:** showing the analytical validity of our architectural design and optimization; and **(c) highly generalizable:** demonstrating robust performance across diverse domains without requiring per-domain retraining, a capability not supported by existing baselines.

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