United States

Recently, both closed-source LLMs and open-source communities have made significant strides, outperforming humans in various general domains. However, their performance in specific professional domains such as medicine, especially within the open-source community, remains suboptimal due to the complexity of medical knowledge. In this paper, we propose CareBot, a bilingual medical LLM, which leverages a comprehensive approach integrating continuous pre-training (CPT), supervised fine-tuning (SFT), and reinforcement learning with human feedback (RLHF). Our novel two-stage CPT method, comprising Stable CPT and Boost CPT, effectively bridges the gap between general and domain-specific data, facilitating a smooth transition from pre-training to fine-tuning and enhancing domain knowledge progressively. We also introduce DataRater, a model designed to assess data quality during CPT, ensuring that the training data is both accurate and relevant. For SFT, we develope a large and diverse bilingual dataset, along with ConFilter, a metric to enhance multi-turn dialogue quality, which is crucial to improving the model&#39;s ability to handle more complex dialogues. The combination of high-quality data sources and innovative techniques significantly improves CareBot&#39;s performance across a range of medical applications. Our rigorous evaluations on Chinese and English benchmarks confirm CareBot&#39;s effectiveness in medical consultation and education. These advancements not only address current limitations in medical LLMs but also set a new standard for developing effective and reliable open-source models in the medical domain. We will open-source the datasets and models later, contributing valuable resources to the research community.

AAAI 2025

CareBot: A Pioneering Full-Process Open-Source Medical Language Model

snlp

generation

It is my great pleasure and honor to welcome you to the 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026), held in San Diego, California, USA, July 2–7, 2026. ACL 2026 continues our fields tradition of excellence in scholarship, innovation, and inclusivity, and I am deeply grateful to the many volunteers who have worked tirelessly to bring this event to life.

It is exciting to see the many developments in the field reflected at our conference, such as the advancement of large language models (born out of our community) into many application directions. This is not without challenges, partly due to unsolved problems, and partly due to misuse of the technology. All this is reflected well at ACL 2026. The conference also reflects that the field is not only about advancing technology, but also the science of fundamentally understanding language and how it is use by many different speaker communities. 
[Full Message from General Chair Philipp Koehn](https://drive.google.com/file/d/1QiJFOmMjvDgsDo3i1XzlQnImxe3RU_Cy/view?usp=sharing) 
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ACL 2026

The 64th Annual Meeting of the Association for Computational Linguistics (ACL 2026) will take place in San Diego, California, from July 2 - 7, 2026.

Recently, both closed-source LLMs and open-source communities have made significant strides, outperforming humans in various general domains. However, their performance in specific professional domains such as medicine, especially within the open-source community, remains suboptimal due to the complexity of medical knowledge. In this paper, we propose CareBot, a bilingual medical LLM, which leverages a comprehensive approach integrating continuous pre-training (CPT), supervised fine-tuning (SFT), and reinforcement learning with human feedback (RLHF). Our novel two-stage CPT method, comprising Stable CPT and Boost CPT, effectively bridges the gap between general and domain-specific data, facilitating a smooth transition from pre-training to fine-tuning and enhancing domain knowledge progressively. We also introduce DataRater, a model designed to assess data quality during CPT, ensuring that the training data is both accurate and relevant. For SFT, we develope a large and diverse bilingual dataset, along with ConFilter, a metric to enhance multi-turn dialogue quality, which is crucial to improving the model's ability to handle more complex dialogues. The combination of high-quality data sources and innovative techniques significantly improves CareBot's performance across a range of medical applications. Our rigorous evaluations on Chinese and English benchmarks confirm CareBot's effectiveness in medical consultation and education. These advancements not only address current limitations in medical LLMs but also set a new standard for developing effective and reliable open-source models in the medical domain. We will open-source the datasets and models later, contributing valuable resources to the research community.

poster

We are pleased to announce the Thirty-Ninth AAAI Conference on Artificial Intelligence (AAAI-25), which will be held in Philadelphia, Pennsylvania at the Pennsylvania Convention Center from February 25 to March 4, 2025.

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-25 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and a range of other activities to be announced.

### [Invited Speakers](https://aaai.org/conference/aaai/aaai-25/aaai-25-invited-speakers/)

Register [here](https://aaai.org/conference/aaai/aaai-25/registration/)

The purpose of the AAAI conference series is to promote research in Artificial Intelligence (AI) and foster scientific exchange between researchers, practitioners, scientists, students, and engineers across the entirety of AI and its affiliated disciplines. AAAI-25 will feature technical paper presentations, special tracks, invited speakers, workshops, tutorials, poster sessions, senior member presentations, competitions, and exhibit programs, and a range of other activities to be announced.



Tactile sensation plays a crucial role in the development of multi-modal large models and embodied intelligence. To collect tactile data with minimal cost as possible, a series of studies have attempted to generate tactile images by vision-to-touch image translation. However, compared to text modality, visual modality-driven tactile generation cannot accurately depict human tactile sensation. In this work, we analyze the characteristics of tactile images in detail from two granularities: object-level (tactile texture, tactile shape), and sensor-level (gel status). We model these granularities of information through text descriptions and propose a fine-grained Text-to-Touch generation method (TextToucher) to generate high-quality tactile samples. Specifically, we introduce a multimodal large language model to build the text sentences about object-level tactile information and employ a set of learnable text prompts to represent the sensor-level tactile information. To better guide the tactile generation process with the built text information, we fuse the dual grains of text information and explore various dual-grain text conditioning methods within the diffusion transformer architecture. Furthermore, we propose a Contrastive Text-Touch Pre-training (CTTP) metric to precisely evaluate the quality of text-driven generated tactile data. Extensive experiments demonstrate the superiority of our TextToucher method.

TextToucher: Fine-Grained Text-to-Touch Generation

Phase imaging is gaining importance due to its applications in fields like biomedical imaging and material characterization. In biomedical applications, it can provide quantitative information missing in label-free microscopy modalities. One of the most prominent methods in phase quantification is the Transport-of-Intensity Equation (TIE). TIE often requires multiple acquisitions at different defocus distances, which is not always feasible in a clinical setting due to hardware constraints. To address this issue, we propose the use of chromatic aberrations to induce the required through-focus images with a single exposure, effectively generating a through-focus stack. Since the defocus distance induced by the aberrations is small, conventional TIE solvers are insufficient to address the resulting artifacts. We propose Zero-Mean Diffusion, a modified version of diffusion models designed for quantitative image prediction, and train it with synthetic data to ensure robust phase retrieval. Our contributions offer an alternative TIE approach that leverages chromatic aberrations, achieving accurate single-exposure phase measurement with white light and thus improving the efficiency of phase imaging. Additionally, we present a new class of diffusion models that are well-suited for quantitative data and have a sound theoretical basis. To validate our approach, we employ a widespread brightfield microscope equipped with a commercially available color camera. We apply our model to clinical microscopy of patients' urine, obtaining accurate phase measurements.

Single Exposure Quantitative Phase Imaging with a Conventional Microscope Using Diffusion Models

Visual Question Answering (VQA) has garnered significant attention as a crucial link between vision and language, aimed at generating accurate responses to visual queries. However, current VQA models still struggle with the challenge of minority class collapse and spurious semantic correlations posed by language bias and imbalanced distributions. To address these challenges, this paper proposes a novel Prompt-Driven Geometric Harmonization (PDGH) paradigm, which integrates both geometric structure and information entropy principles to enhance the ability of VQA models to generalize effectively across diverse scenarios. Specifically, our PDGH approach is meticulously designed to generate image-generated prompts that are guided by specific question cues, facilitating a more accurate and context-aware understanding of the visual content. Moreover, we project the prompt-visual-question and visual-question joint representations into a unified hypersphere space, applying feature weight self-orthogonality and prompt-information entropy correction constraints to optimize the margin, further alleviating minority class collapse and correcting language bias. To maintain the geometric integrity of the representation space, we introduce multi-space geometric contrast constraints to minimize the impact of spurious priors introduced during training.  Finally, a semantic matrix is constructed for the coordinated joint representation to ensure that the learned instances are semantically consistent and improve reasoning ability. Extensive experiments on various benchmark datasets across modalities demonstrate the consistent superiority of our PDGH approach over existing state-of-the-art baselines.

Towards Robust Visual Question Answering via Prompt-Driven Geometric Harmonization

Learning with softmax cross-entropy on one-hot labels often leads to overconfidence on the correct class. While label smoothing regulates this overconfidence by redistributing $\alpha$ confidence from the correct class to other incorrect classes, it compromises the representation in the logits about the similarity between samples of different classes and may hurt calibration if a larger $\alpha$ is required for high accuracy. To overcome these limitations, we propose a Virtual Smoothing label that redistributes certain confidence from the correct class to additional Virtual Smoothing (VS) classes to regularize overconfidence. In VS labels, the VS class nodes act as adversaries to the original class nodes, enforcing regularization by clustering samples across all classes. The zero confidence of each incorrect class also allows the incorrect logits to be different from each other without erasing information about sample similarities. The prediction probability can still approach 1 when applying softmax to the logits of the original real classes, which avoids harming but consistently improves calibration. Experiments show that VS labels consistently improve accuracy and calibration while providing better logits for improved knowledge distillation. Additionally, VS labels exhibit effectiveness in improving adversarial training, robust distillation, and out-of-distribution detection.

Training Deep Neural Networks with Virtual Smoothing Classes

High-resolution Vision-Language Models (VLMs) have been widely used in multimodal tasks to enhance accuracy by preserving detailed image information. However, these models often generate excessive visual tokens due to encoding multiple partitions of the input image. Processing these excessive visual tokens is computationally challenging, especially in resource-constrained environments with commodity GPUs. To support high-resolution images while meeting resource constraints, we propose High-Resolution Early Dropping (HiRED), a token-dropping scheme that operates within a fixed token budget before the Large Language Model (LLM) stage. HiRED can be integrated with existing high-resolution VLMs in a plug-and-play manner, as it requires no additional training while still maintaining superior accuracy. We strategically use the vision encoder’s attention in the initial layers to assess the visual content of each image partition and allocate the token budget accordingly. Then, using the attention in the final layer, we select the most important visual tokens from each partition within the allocated budget, dropping the rest. Empirically, when applied to LLaVA-Next-7B on NVIDIA TESLA P40 GPU, HiRED with a 20\% token budget increases token generation throughput by 4.7$\times$, reduces first-token generation latency by 15 seconds, and saves 2.3 GB of GPU memory for a single inference.

HiRED: Attention-Guided Token Dropping for Efficient Inference of High-Resolution Vision-Language Models

Quantum computing promises to revolutionize various fields, yet the execution of quantum programs necessitates an effective compilation process. This involves strategically mapping quantum circuits onto the physical qubits of a quantum processor. The qubits' arrangement, or topology, is pivotal to the circuit's performance, a factor that often defies traditional heuristic or manual optimization methods due to its complexity. In this study, we introduce a novel approach leveraging reinforcement learning to dynamically tailor qubit topologies to the unique specifications of individual quantum circuits, guiding algorithm-driven quantum processor topology design for reducing the depth of mapped circuit, which is particularly critical for the output accuracy on noisy quantum processors. Our method marks a significant departure from previous methods that have been constrained to mapping circuits onto a fixed processor topology. Experiments demonstrate that we have achieved notable enhancements in circuit performance, with a minimum of 20\% reduction in circuit depth in 60\% of the cases examined, and a maximum enhancement of up to 46\%. Furthermore, the pronounced benefits of our approach in reducing circuit depth become increasingly evident as the scale of the quantum circuits increases, exhibiting the scalability of our method in terms of problem size. This work advances the co-design of quantum processor architecture and algorithm mapping, offering a promising avenue for future research and development in the field.

AI-Powered Algorithm-Centric Quantum Processor Topology Design

Text-attributed graphs have recently garnered significant attention due to their wide range of applications in web domains. Existing methodologies employ word embedding models for acquiring text representations as node features, which are subsequently fed into Graph Neural Networks (GNNs) for training. Recently, the advent of Large Language Models (LLMs) has introduced their powerful capabilities in information retrieval and text generation, which can greatly enhance the text attributes of graph data. Furthermore, the acquisition and labeling of extensive datasets are both costly and time-consuming endeavors. Consequently, few-shot learning has emerged as a crucial problem in the context of graph learning tasks. In order to tackle this challenge, we propose a lightweight paradigm called LLM4NG, which adopts a plug-and-play approach to establish supervision signals by leveraging Large Language Models (LLMs) for node generation. Specifically, we utilize LLMs to extract semantic information from the labels and generate samples that belong to these categories as exemplars. Subsequently, we employ an edge predictor to capture the structural information inherent in the raw dataset and integrate the newly generated samples into the original graph. This approach harnesses LLMs for enhancing class-level information and seamlessly introduces labeled nodes and edges without modifying the raw dataset, thereby facilitating the node classification task in few-shot scenarios. Extensive experiments demonstrate the outstanding performance of our proposed paradigm, particularly in low-shot scenarios. For instance, in the 1-shot setting of the ogbn-arxiv dataset, LLM4NG achieves a 76% improvement over the baseline model.

Leveraging Large Language Models for Node Generation in Few-Shot Learning on Text-Attributed Graphs

Source-Free Domain Adaptation (SFDA) aims to transfer a pre-trained source model to the unlabeled target domain without accessing the source data, thereby effectively solving labeled data dependency and domain shift problems. However, the SFDA setting faces a bottleneck due to the absence of supervisory information. To mitigate this problem, Active Learning (AL) is introduced to combine with SFDA, endeavoring to actively label a small set of the most high-quality target points so that models with satisfactory performance can be obtained at an acceptable cost. Nevertheless, several issues remain unresolved, namely when to query new labels during training, what kind of samples deserve labeling to ensure rich information, and where the labels should be distributed to guarantee diversity. Thus we elaborate ActiveSFDA to omni bearing address the “When, What, and Where” problems about Active points querying in Source-Free Domain Adaptation for cross-modal 3D semantic segmentation. The method consists of three main components: Query Decider, Point Ranker, and Budget Slicer. The Query Decider determines the optimal timing to query new points by fitting the validation curves during training. The Point Ranker nominates points for annotation by calculating the ambiguity of neighboring points in the feature space. The Budget Slicer allocates the annotation quota, i.e., labeling percentage of the point cloud, to different semantic regions by utilizing the advanced 2D semantic segmentation capabilities of the Segment Anything Model (SAM). Extensive experiments demonstrate the effectiveness of our proposed method, achieving up to 99.64% of fully supervised performance with only 3% of labels, and consistently outperforming comparison methods across various scenarios.

Omni-Query Active Learning for Source-Free Domain Adaptive Cross-Modality 3D Semantic Segmentation

Unsupervised domain adaptation (UDA) is a machine learning approach designed to minimize reliance on labeled data by aligning features between a labeled source domain and an unlabeled target domain, thereby reducing feature discrepancies, which is efficient for multivariate time series (MTS) prediction. However, most MTS UDA methods focus solely on aligning intra-series temporal features, overlooking the valuable information in inter-series dependencies. Research has highlighted that analyzing decomposed frequency dependencies in time series can reveal significant trends, noise patterns, and intricate temporal details. To address these unexplored frequency dependencies, we introduce the Frequency Graph Discovery Module (FGD), which uncovers and aligns shared frequency information and correlations across domains. Additionally, we propose a Frequency-Contextual Contrastive Learning (FCCL) framework to better capture and align frequency-contextual representations in multivariate time series, ensuring the extraction of label-invariant information for prediction. Furthermore, considering existing models overlooking the valuable and abundant information outside source and target dataset, we enhance the MTS UDA prediction model with a Language-guided Adversary Alignment (LAA) module, which leverages the advancement and capabilities of Large Language Models (LLMs) to get text-encoded labeled embeddings and align the classification features, thereby improving prediction accuracy. Our model achieves state-of-the-art results on three public multivariate time-series datasets for unsupervised domain adaptation, as demonstrated by empirical evidence.

Enhancing Multivariate Time-Series Domain Adaptation via Contrastive Frequency Graph Discovery and Language-Guided Adversary Alignment

Graph contrastive learning (GCL) has drawn much research attention for its ability to learn node representations in a self-supervised manner. However, the homophily assumption inherent in GNN encoders limits the direction (macro-level) and the process (micro-level) of message passing in current GCL frameworks, impairing the expressive power of GCL in non-homophilous graphs. This paper presents a novel framework that employs Macro and Micro Message Passing in GCL ($\mathrm{M}^3\mathrm{P}\text{-}\mathrm{GCL}$) to overcome these limitations and advance performance in both homophilous and non-homophilous graphs. Specifically, at the macro-level, we integrate both structural and attribute views to enhance the direction of message passing, and employ a Aligned Priority-Supporting View Encoding (APS-VE) strategy to facilitate contrastive training; at the micro-level, we propose an Adaptive Self-Propagation (ASP) strategy based on role segmentation of self-loop to diversify the process of message passing in the encoder. These enhancements effectively address the limitations imposed by the homophily assumption. Experiments demonstrate that $\mathrm{M}^3\mathrm{P}\text{-}\mathrm{GCL}$ outperforms both supervised and unsupervised baselines in the node classification task on various datasets with different levels of homophily.

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